Bile acids drive chemotaxis of Clonorchis sinensis juveniles to the bile duct

Effects of acid pepsin pretreatment, bile acids and reductants on the excystation of Clonorchis sinensis

The effects of acid pepsin pretreatment, bile acids and reductants on the excystation of Clonorchis sinensis metacercariae were studied. The velocities of metacercarial excystation, digestion of the metacercarial outer layer and tryptic BAEE hydrolysis were measured in various media. Pretreatment with acid or acid pepsin accelerated the excystation, but was not required under adequate tryptic a...

Bile acids in the rat: studies in experimental occlusion of the bile duct.

Bile acids in the plasma, urine, and small intestine of adult male rats with occluded bile ducts have been studied using a method of high specificity for their determination. After bile duct ligation cholic acid rapidly accumulates in the plasma for 8 hr, remains high for a further 8 hr, and subsequently diminishes; bile acids disappear from the small intestine. During the first 12 hr after bil...

Management of Bile Duct Problems Treatment Overview Bile Duct Obstruction

Tracing of the Bile-Chemotactic Migration of Juvenile Clonorchis sinensis in Rabbits by PET-CT

BACKGROUND Adult Clonorchis sinensis live in the bile duct and cause clonorchiasis. It is known that the C. sinensis metacercariae excyst in the duodenum and migrate up to the bile duct through the common bile duct. However, no direct evidence is available on the in vivo migration of newly excysted C. sinensis juveniles (CsNEJs). Advanced imaging technologies now allow the in vivo migration and...

The Estimation of Bile Acids in Bile

In a recent paper Foster and Hoop& (1) have described a rapid method for the estimation of bile acids in dog bile. The method depends on the fact that the two bile acids usually found in dog bile, viz. taurocholic and taurocholeic, on hydrolysis with alkali give taurine, which yields its nitrogen quantitatively in 4 minutes when shaken with HN02. Taurocholic and taurocholeic acids do not react ...